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National Institute for Research in Tuberculosis (NIRT), Chennai, Tamil Nadu

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Location
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Area of Operation:
Chennai :
50 wards of Chennai city, Tamil Nadu
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Contact Information:
Dr. Soumya Swaminathan, Scientist 'G'
National Institute for Research in Tuberculosis
(Formerly The Tuberculosis Research Centre)
No.1, Sathiyamoorthy Road, Chetput,
Chennai - 600 031, India

imgPhone : +91-44-28369500

imgFax : +91-44-28362528

imgE-mail : This email address is being protected from spambots. You need JavaScript enabled to view it.

imgWebsite :http;//www.trc-chennai.org

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Activity
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TB disease burden surveys (prevalence and incidence) in rural and urban areas
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Impact evaluation of TB control programs
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Health seeking behaviour & awareness of tuberculosis among migrant brick kiln workers in rural Tiruvallur district
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Public Health Areas
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  • » Disease Surveillance
  • » Communicable Diseases
  • » Service Delivery
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Organizational Overview
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Legal Status

Central Government Organization

Year Launched

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1956

Stage

Well-established, with goal of better publicity for their work, and greater collaboration in converting basic science advancements into tangible public health benefits.

Income level of target population

All levels

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Summary
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The Tuberculosis Chemotherapy Centre (as the NIRT was then known) was set up in 1956 as a result of a collaboration between ICMR (Indian Council of Medical Research), BMRC (British Medical Research Council), USPHS (United States Public Health Service), and the Government of Tamil Nadu. It became the Tuberculosis Research Centre (TRC) in the 1970s, and was renamed the National Institute for Research in Tuberculosis (NIRT) recently. NIRT’s vision is to undertake high quality research in Tuberculosis that is relevant to both national and global programmatic needs.

The first research activity undertaken in 1956 (‘The Madras Study’) was meant to compare the efficacy of drug treatment at home, for isolation in sanatoria during duration of treatment for TB patients. The study found that cure rates were the same in both settings, and there was no greater contact risk by leaving patients at home. The results of this trial prompted OPD treatment of TB patients.

Clinical trials have formed the backbone of NIRT activities throughout its history, with emphasis placed on shortening the duration of treatment regiments, children’s TB and HIV-TB coinfection. NIRT is currently working to shorten the TB regiment from 6 months to 4 months by working with a class of drugs called fluoroquinolones. All this is in addition to many basic science and laboratory-based research activities undertaken in NIRT.

On the epidemiology front, NIRT has worked with the Central Government in conducting TB surveys and prevalence estimates, as India has no rigorous nationwide system for generating data on TB mobidity, mortality, and heterogeneity.

A BCG trial (largest vaccine trial anywhere in the world) was...

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Target Geography
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  • » Urban (Chennai city)
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Demographic Profile
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  • » Male
  • » Female
  • » Adolescents and young people
  • » Women of reproductive age
  • » More than 60 years (elderly population)
  • » 15 years and older
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Primary Funding Agencies
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Indian Government
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Scale
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Number of Publications (2000-2011)
  • » National Journals: 219
  • » International Journals: 338
Non-Technical Staff

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>20

Technical Staff

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>20

Study Population

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26,259

Future Plans
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NIRT plans to move its activities towards greater interaction with public health implementers, and to address the operational challenges of TB control programs.
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